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100 Pulse Longevity Program

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100 Pulse Longevity Program

Who Is This Program For?

  • Adults aged 35 and above who want to take a proactive approach to heart health
  • Individuals with cardiovascular risk factors, such as:
    • a family history of heart disease
    • high cholesterol or high blood sugar levels
    • high blood pressure, or a history of hypertension that is currently controlled
    • overweight or obesity
    • a history of diabetes or metabolic concerns
  • Executives and high performers who want to optimize their health for peak performance
  • Longevity enthusiasts who are serious about long-term health and disease prevention
  • Individuals with warning symptoms such as easy fatigue, shortness of breath, or chest discomfort
  • Anyone who wants to understand their true cardiovascular risk through testing that goes beyond standard health check-ups

What Can This Program Help With?

Primary Prevention

  • Detect cardiovascular risk 10–20 years before symptoms appear
  • Address key risk factors before they develop into heart disease, diabetes, or vascular blockage
  • Slow down or potentially reverse early vascular damage

Longevity Optimization

  • Support a longer lifespan and better quality of life
  • Reduce the risk of heart attack and stroke
  • Improve energy, physical strength, and work performance
  • Slow age-related decline in the heart and blood vessels

Secondary Prevention

  • Systematically manage cholesterol, blood pressure, and blood sugar
  • Help prevent complications from existing medical conditions
  • Provide continuous monitoring and treatment adjustment over time

Comprehensive Testing

Basic Screening and Initial Assessment

  • General health screening (vital signs)
  • Lifestyle assessment, including sleep, stress, and diet
  • Risk factor questionnaire screening: Framingham / ASCVD score
  • Body Composition Analysis
  • Detailed Blood Pressure Monitoring

Advanced Longevity Biomarkers

Lipid and Vascular Health

  • Complete Lipid Profile(Total Cholesterol, LDL, HDL, Triglycerides)
  • Apolipoprotein B (ApoB) – a more accurate cardiovascular risk marker than LDL alone
  • Lipoprotein(a) – evaluates inherited cardiovascular risk
  • ApoB:ApoA1 Ratio – assesses vascular risk balance
  • Fibrinogen – associated with blood clotting risk

Glucose and Metabolic Health

  • Fasting Blood Sugar (FBS)
  • HbA1c – 3-month average blood glucose marker
  • Fasting Insulin – helps assess insulin sensitivity before diabetes develops
  • Urine Organic Profile
  • Fasting Lactate or Pyruvate:Lactate Ratio

Cardiac and Inflammatory Health

  • hs-Troponin – evaluates whether there may be heart muscle cell injury
  • NT-proBNP – reflects cardiac function
  • hs-CRP – vascular inflammation marker
  • Homocysteine – related to metabolism and vascular health
  • ADMA / SDMA – markers related to vascular function
  • Myeloperoxidase (MPO) – indicates vascular inflammation

Other General Health Markers Relevant to Heart Health

  • CBC – complete blood count
  • Liver Function Test
  • Kidney Function(BUN, Creatinine, eGFR, Albumin:Creatinine Ratio)
  • Uric Acid
  • Thyroid Function(Free T3, Free T4, TSH)
  • Vitamin D – important for cardiovascular health
  • Omega-3 Index – reflects beneficial fatty acid levels in cells

Comprehensive Treatment Approach

Medical Management

Medication is prescribed when clinically appropriate, based on each individual’s risk profile and health status.

  • Lipid-lowering therapy(Statins, Red Yeast Rice, Ezetimibe, PCSK9 inhibitors)
  • Blood pressure medications(selected according to the individual’s condition)
  • Blood sugar management(Metformin for insulin resistance, where appropriate)
  • Aspirin in selected cases
  • Additional medications based on complications or associated conditions

Advanced Supplementation Protocol

Evidence-based supplementation is personalized according to blood test results and individual needs.

  • Omega-3 (EPA/DHA) 2–4 g/day – supports inflammation control and cardiovascular protection
  • Vitamin D3 + K2 – supports vascular and bone health
  • Magnesium Glycinate – supports heart rhythm and blood pressure balance
  • CoQ10 – supports heart cell energy production, especially important for patients taking statins
  • NAC (N-Acetyl Cysteine) – supports antioxidant defense and homocysteine balance
  • Methylfolate + B12 – supports homocysteine metabolism
  • Berberine or Alpha-Lipoic Acid – supports insulin sensitivity
  • L-Citrulline or L-Arginine – supports vascular dilation and circulation

Personalized Nutrition Program

  • Anti-inflammatory Mediterranean–DASH hybrid diet
  • Macronutrient optimization based on the individual’s metabolic profile
  • Time-restricted eating (such as 16:8), when appropriate
  • Nutritionist consultations: twice in the first month, then monthly thereafter
  • Meal planning and grocery guidance

Exercise Prescription

The goal is to improve VO₂ max by at least 10–15%, one of the strongest indicators of long-term health and longevity.

  • Zone 2 Cardio3–4 sessions per week, 45–60 minutes eachWalking, jogging, or cycling at a conversational pace to build fat-burning capacity and cardiovascular endurance
  • Resistance Training2–3 sessions per weekSupports muscle mass, increases metabolic health, and helps prevent age-related decline
  • HIIT (High-Intensity Interval Training)1–2 sessions per weekHelps improve VO₂ max and cardiovascular performance

Lifestyle Optimization

Sleep Optimization

  • Target: 7–9 hours of quality sleep per night
  • Sleep hygiene protocol
  • Ongoing sleep quality monitoring

Stress Management

  • Meditation and mindfulness practices
  • Breathing exercises
  • Work–life balance strategies
  • HRV (Heart Rate Variability) training

Smoking Cessation and Alcohol Moderation

  • Smoking cessation support, when needed
  • Guidance on appropriate alcohol intake

Key Performance Indicators

Primary Endpoints

  • Reduction in cardiovascular risk markers
  • Improvement in blood pressure, lipid profile, and glucose regulation
  • Better vascular and metabolic health outcomes

Secondary Endpoints

  • Improvement in body composition
  • Increased VO₂ max and physical performance
  • Better sleep, energy, and stress resilience
  • Improved long-term adherence to heart-healthy lifestyle habits

Biomarker

Optimal Target

Why It Matters

ApoB

< 60 mg/dL

The most accurate marker of cardiovascular risk

hs-CRP

< 1 mg/L

Indicates inflammation in the blood vessels

HbA1c

< 5.4%

Reflects long-term blood sugar control

Fasting Insulin

< 5 µIU/mL

Indicates insulin sensitivity (before diabetes develops)

Blood Pressure

< 120/80 mmHg

The blood pressure range associated with the lowest cardiovascular risk

Homocysteine

< 8 µmol/L

Reflects vascular health and metabolic function

Indicator

Target

Monitoring Frequency

Carotid IMT

No progression or reduced thickness

Annually

Body Composition

Reduced visceral fat, increased muscle mass

Every 3 months

VO2 Max

Increase by 10–15%

Every 6 months

Omega-3 Index

> 8%

Every 6 months

Vitamin D

40-60 ng/mL

Every 6 months

HRV (Heart Rate Variability)

Improvement

Weekly(self-monitoring)

Lifestyle Metrics

  • Sleep Quality Score: > 80%
  • Exercise Compliance: > 90%
  • Nutrition Adherence: > 85%
  • Stress Level: Reduced (assessed through HRV)
  • Medication/Supplement Compliance: 100%

Follow-up Schedule

Months 1–3: Intensive Phase

  • Weekly check-ins (online or in person)
  • Weekly home blood pressure monitoring
  • Monitoring of medication and supplement adherence
  • Nutritionist follow-up every 2 weeks
  • Exercise tracking and plan adjustment as needed

Month 3: First Reassessment

  • Follow-up blood testing panel, including:
    • Lipid panel
    • ApoB
    • HbA1c
    • hs-CRP
  • Body composition analysis
  • Blood pressure and ECG check
  • Progress evaluation and treatment plan adjustment

Month 6: Mid-Year Review

  • Comprehensive blood testing(excluding markers that do not typically change rapidly, such as Lp(a))
  • Body composition analysis
  • VO₂ max testing (if available)
  • Review of progress and adjustment of the treatment plan for the second half of the year

Month 12: Annual Comprehensive Review

  • Repeat all baseline assessments
  • Carotid IMT to assess progression or regression
  • ABI
  • Comparison of all biomarkers over time
  • Planning for the following year
  • Celebrate success

Choose the Package That Suits You

ESSENTIAL LONGEVITY (Starting Package)

Price: THB 25,000–35,000 / year

  • Complete baseline assessment
  • Comprehensive blood work panel
  • Follow-up every 6 months
  • 4 physician consultations per year
  • Online support

Suitable for: Individuals who are beginning to take their heart health seriously.

PREMIUM LONGEVITY

Price: THB 50,000–70,000 / year

  • Everything included in Essential
  • Intensive first 3 months with weekly support
  • Monthly check-ins throughout the year
  • Personalized supplement protocol
  • Exercise and nutrition coaching
  • 24/7 online consultation access
  • Priority appointments

Suitable for: Individuals seeking faster results and a more hands-on level of care.

ULTIMATE LONGEVITY

Price: THB 100,000+ / year

  • Everything included in Premium
  • Advanced testing (VO₂ max, advanced biomarkers)
  • Quarterly comprehensive assessments
  • Dedicated health coach
  • Genetic testing (optional add-on)
  • Priority access to all services
  • Home visit options
  • VIP concierge health service

Suitable for: Executives and high performers who want to optimize their health to the highest level.

Frequently Asked Medical Questions from EPIOS

This compilation of frequently asked questions about preventive healthcare, treatment approaches, programs, and service procedures helps you understand important information and prepare confidently for receiving care.

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